Clinical trials

7

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase II Trial of LM103 for Adjuvant Treatment in Patients With Non-small Cell Lung Cancer

After receiving neoadjuvant treatment with PD-1 antibody and undergoing radical resection, a total 36 to 45 NSCLC patients who met the inclusion criteria, will be randomly assigned in a 1:1:1 ratio to the experimental group 1, experimental group 2 and the control group in this Phase IIa clinical trial. The study will be followed up until 24 to 36 months after treatment.

Participants needed: 45
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Suzhou BlueHorse Therapeutics Co., Ltd.Updated: May 13, 2026Locations: 5
Eligibility criteria

At the date of signing Informed Consent Form (ICF), 18 ~75 years old, male or fe... [+6]

A history of other malignant tumors within the past 5 years, excluding malignant... [+16]

Status: Recruiting

A Phase II Trial of LM103 in Advanced Melanoma

A total of 92 subjects with advanced melanoma who met the inclusion criteria will be randomly assigned in a 1:1 ratio to the experimental group and the control group in this phase II trial. The study will be followed up until 24 months after treatment.

Participants needed: 92
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Suzhou BlueHorse Therapeutics Co., Ltd.Updated: May 12, 2026Locations: 13
Eligibility criteria

At the date of signing Informed Consent Form (ICF), 18 ~75 years old, male or fe... [+7]

A history of other malignant tumors within the past 5 years, excluding malignant... [+17]

Status: Recruiting

An Exploratory Clinical Study to Evaluate the Safety, Tolerability, Immune Response and Preliminary Efficacy of LM103 Injection in Combination With PD-1 in Patients With Advanced Solid Tumours

This is an exploratory clinical study evaluating the safety, tolerability, immune response and preliminary efficacy of LM103 Injection in combination with PD-1 in patients with advanced solid tumours. The research treatment includes LM103 injection, IL-2 therapy, PD-1 therapy,fludarabine and cyclophosphamide.

Participants needed: 10
Trial details
Phase: Early Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Suzhou BlueHorse Therapeutics Co., Ltd.Updated: Nov 20, 2024Locations: 1
Eligibility criteria

The expected survival time is not less than 3 months. [+5]

Have a medical history of other malignant tumors other than the disease under st... [+3]

Status: Recruiting

An Investigator-initiated Clinical Study of LM303 Injection for the Treatment of Advanced Solid Tumours

This is a single-arm, open-label, exploratory study to evaluate safety and efficacy of LM303 Injection in patients with advanced solid tumors. The purpose of this study is to evaluate the safety and tolerability, antitumor activity and immunoreactivity.

Participants needed: 10
Trial details
Phase: Early Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Suzhou BlueHorse Therapeutics Co., Ltd.Updated: Nov 19, 2024Locations: 1
Eligibility criteria

AJCC (V8) stage III or IV melanoma, non-small cell lung cancer, cervical cancer... [+7]

Suffering from active or previous autoimmune diseases ; [+6]

Status: Not yet recruiting

A Clinical Study on LM103 Injection for the Treatment of Advanced Solid Tumors

This study is an open exploratory clinical study to evaluate the safety, tolerance, immune response, and initial efficacy of autologous tumor infiltrating lymphocyte LM103 injection in advanced solid tumor patients. The research treatment includes fludarabine and cyclophosphamide, autologous tumor infiltrating lymphocytes (TILs) infusion, and Interleukin-2 therapy.

Participants needed: 5
Trial details
Phase: Early Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Suzhou BlueHorse Therapeutics Co., Ltd.Updated: Aug 2, 2023
Eligibility criteria

The expected survival time is not less than 6 months. [+5]

Have a medical history of other malignant tumors other than the disease under st... [+3]

Status: Not yet recruiting

A Clinical Study on TILs for the Treatment of Advanced Solid Tumors

This study is an open exploratory clinical study to evaluate the safety, tolerance, immune response, and initial efficacy of autologous tumor infiltrating lymphocyte LM103 injection in advanced solid tumor patients . The research treatment includes fludarabine and cyclophosphamide, autologous tumor infiltrating lymphocytes (TILs) infusion, and Interleukin-2 therapy.

Participants needed: 20
Trial details
Phase: Early Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Suzhou BlueHorse Therapeutics Co., Ltd.Updated: Aug 2, 2023
Eligibility criteria

The expected survival time is not less than 3 months. [+5]

Have a medical history of other malignant tumors other than the disease under st... [+3]

Status: Recruiting

A Clinical Study of LM103 Injection in the Treatment of Advanced Solid Tumors

This is a single-arm, open-label, exploratory study to evaluate safety and efficacy of LM103 Injection in patients with advanced solid tumors. The purpose of this study is to evaluate the safety and tolerability, antitumor activity and immunoreactivity.

Participants needed: 15
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Suzhou BlueHorse Therapeutics Co., Ltd.Updated: Aug 2, 2022Locations: 1
Eligibility criteria

AJCC (V8) stage III or IV melanoma, non-small cell lung cancer, cervical cancer... [+7]

Suffering from active or previous autoimmune diseases ; [+6]