Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

The goal of this clinical trial is to study the combination of SX-682 plus enzalutamide in men with metastatic castration resistant prostate cancer (mCRPC) who have failed prior therapy with androgen receptor pathway inhibitors.

Participants needed: 53
Trial details
Phase: Phase 2Age: 18+Biological sex: MaleType: InterventionalSponsor: Syntrix Biosystems, Inc.Updated: Jun 2, 2026Locations: 6
Eligibility criteria

Signed and dated Institutional Review Board (IRB)/Independent Ethics Committee (... [+15]

Prior treatment with docetaxel or marketed antibody within 4 weeks of first dose... [+24]

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Status: Recruiting

Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome

This study will determine the safety profile, maximum tolerated dose (MTD), dose-limiting toxicities (DLT), and recommended Phase 2 dose (RP2D) of SX-682 in the treatment of patients with Myelodysplastic Syndromes (MDS).

Participants needed: 151
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Syntrix Biosystems, Inc.Updated: Dec 23, 2025Locations: 7
Eligibility criteria

Diagnosis of MDS by World Health Organization criteria, and either [+12]

Use of chemotherapeutic agents or experimental agents for MDS within 14 days of... [+14]

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