Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of Safety and Efficacy of TC011 in the Relapsed/Refractory Large B Cell Non-Hodgkin Lymphoma Patients

This is a multi-center, phase I/II study to determine the safety and efficacy of TC011(CD19 Targeted CAR-T) in adult patients with relapsed or refractory large B-cell non -hodgkin lymphoma.

Participants needed: 98
Trial details
Phase: Phase 1, Phase 2Age: 19+Biological sex: AllType: InterventionalSponsor: TICAROS Co., Ltd.Updated: Mar 16, 2026Locations: 1
Eligibility criteria

≥19 years old, ECOG 0-2, life expectancy ≥12 weeks [+7]

Unresolved ≥Grade 2 toxicities from prior therapy [+12]

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Status: Not yet recruiting

Efficacy and Safety of TC011 in Relapsed or Refractory Follicular Lymphoma

This Phase II, multi-center, single-arm, open-label study evaluates the efficacy and safety of TC011, a CD19-targeted CAR-T cell therapy, in adult patients with relapsed or refractory follicular lymphoma (Grade 1, 2, or 3a). The primary endpoint is objective response rate (ORR) assessed by independent review using the Lugano 2014 classification.

Participants needed: 40
Trial details
Phase: Phase 2Age: 19+Biological sex: AllType: InterventionalSponsor: TICAROS Co., Ltd.Updated: Jan 22, 2026
Eligibility criteria

Ability to provide written informed consent. [+9]

Histologic transformation to diffuse large B-cell lymphoma or follicular lymphom... [+12]

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