Health Trials

Clinical trials

3

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities

Phase 1 and 2 trial to study the safety, pharmacokinetics, and efficacy of TAS0953/HM06 in patients with advanced solid tumors with RET gene abnormalities. Phase 1 aims to determine the Maximum Tolerated Dose (MTD) and identify the Recommended Phase 2 Dose (RP2D) to be used in phase 2.

Participants needed: 244
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Taiho Pharmaceutical Co., Ltd.Updated: Mar 3, 2026Locations: 21
Eligibility criteria

Eastern Cooperative Oncology Group (ECOG) performance score of 0 or 1 [+19]

Investigational agents or anticancer therapy within 5 half-lives prior to the fi... [+6]

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Status: Recruiting

A Phase 1 Trial of ASTX030 in Patients With Myelodysplastic Syndrome

The purpose of this study is to identify the doses of the oral azacitidine formulations and cedazuridine (CED) tablets which achieve a total AUC for AZA comparable to that for AZA injection at 75 mg/m2

Participants needed: 40
Trial details
Phase: Phase 1Age: 20+Biological sex: AllType: InterventionalSponsor: Taiho Pharmaceutical Co., Ltd.Updated: Dec 3, 2025Locations: 10
Eligibility criteria

Patients aged 20 years or older [+13]

Patients who are unlikely to respond to AZA [+18]

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Status: Recruiting

AB122 Platform Study

This is a phase 1, non-randomized open-label, multicenter platform study designed to evaluate the tolerability and safety of AB122 in patients with malignancies specified in each cohort.

Participants needed: 917
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Taiho Pharmaceutical Co., Ltd.Updated: Sep 25, 2024Locations: 9
Eligibility criteria

Is male or female aged ≥ 18 years at the time of informed consent; Willing and a... [+56]

History or current evidence of cardiac arrhythmia and/or conduction abnormality:... [+21]

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