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Condition / disease
Location
Status: Recruiting

Development and Validation of a Postoperative Re-fracture Risk Model for Osteoporotic Spinal Fractures

In this project, IDEAL-IQ technology and PDFF and R2\* image-based imaging methods are used to analyze the intrinsic relationship between preoperative vertebral bone marrow fat content, magnetic susceptibility properties of bone tissue and bone strength (bone volume and bone mass), to explore the mechanism of vertebral re-fracture after PVP / PKP, and to explore the imaging markers for the risk of postoperative vertebral re-fracture after PVP / PKP. To construct a precise and individualized risk assessment model of vertebral re-fracture after PVP/ PKP by combining clinical risk factors, preoperative quantitative MRI parameters (PDFF, R2\*) and imaging characteristics, so as to achieve the goal of objectively and accurately evaluating the risk of vertebral re-fracture at the early stage of the postoperative period (1 year).

Participants needed: 560
Trial details
Age: 50-90Biological sex: AllType: InterventionalSponsor: The Seventh Affiliated Hospital of Sun Yat-sen UniversityUpdated: Apr 23, 2024Locations: 1
Eligibility criteria

Patients diagnosed with osteoporotic vertebral fractures of the thoracic and lum... [+2]

History of severe scoliosis, vertebroplasty, or internal spinal fixation; [+2]