Status: Recruiting
Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections
Haematopoietic stem cell transplantation (HSCT) can expose patients to a transient but marked immunosuppression, during which viral infections are an important cause of morbidity and mortality. Adoptive transfer of virus-specific T cells is an attractive approach to restore protective T-cell immunity in patients with refractory viral infections after allogeneic HSCT. The aim of this Phase III trial is to confirm efficacy of this treatment in children and adults.
Participants needed: 149
Trial details
Phase: Phase 3Age: 2+Biological sex: AllType: InterventionalSponsor: Tobias FeuchtingerUpdated: Jul 18, 2025Locations: 33
Eligibility criteria
Adult or paediatric patients (> 2 months of age) after allogeneic stem cell tran... [+2]
Patient with acute GvHD > grade II or extensive chronic GvHD at the time of IMP... [+11]