Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Radial vs Vena No-Touch Assessment

This study examines the outcomes of coronary artery bypass grafting (CABG) in women at 1 year after surgery. A randomized controlled trial is planned, including a comparative analysis of two observed groups depending on the chosen conduit for revascularization of the circumflex artery. The main group is supposed to include 55 patients undergoing CABG with the use of the radial artery, while the control group will include 55 patients undergoing CABG with the use of the great saphenous vein prepared using the no-touch technique.

Participants needed: 110
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Tomsk Cardiology Research InstituteUpdated: Apr 27, 2026Locations: 1
Eligibility criteria

Three-vessel disease involving the target circumflex artery with stenosis ≥70% a... [+3]

Previous cardiac surgery of any type, including CABG [+7]

Status: Recruiting

Full Sternotomy vs Mini-sternotomy for Ascending Aortic Pathology

This study investigates outcomes after hemiarch repair in patients with chronic ascending aortic disease. The patients will be divided into two groups according to surgical approach: 100 patients will undergo hemiarch repair via full sternotomy (FS group) and 100 patients will receive hemiarch repair via J-shaped mini-sternotomy (MS group). Early and late outcomes will be recorded.

Participants needed: 200
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Tomsk Cardiology Research InstituteUpdated: Feb 5, 2026Locations: 1
Eligibility criteria

Signed informed consent. [+1]

Acute aortic dissection or urgent/emergent cases. [+3]

Status: Recruiting

The Effect of Colchicine on the Occurrence of Atrial Fibrillation After Cardiac Surgery

Development of a new comprehensive method for perioperative prevention of atrial fibrillation paroxysms in cardiac surgery patients at the hospital stage. It is planned to recruit 70 patients who will undergo pericardial fenestration during the operation using the original technique during coronary artery bypass grafting (Patent No. 2647626 C1 Russian Federation), and will be prescribed colchicine (the drug "Colchicum-dispert") in the perioperative period in order to prevent the development of paroxysms of atrial fibrillation in the postoperative period, and 70 cardiac surgery patients operated on using the standard technique (without performing the pericardial fenestration procedure intraoperatively), receiving non-steroidal anti-inflammatory drugs in the postoperative period.

Participants needed: 140
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Tomsk Cardiology Research InstituteUpdated: Sep 9, 2025Locations: 1
Eligibility criteria

Elective coronary artery bypass grafting on pump; [+1]

Reduced left ventricular ejection fraction (≤35%); [+9]