Clinical trials

4

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Optimal Intensity of Reactive Balance Training for Healthy Older Adults

Falls in daily life are a serious risk for older adults. A new type of balance training, called reactive balance training (RBT) involves people losing balance many times so that they can practice fast balance reactions, like stepping reactions. Differences in training program features might explain differences in the results of previous RBT studies. Training intensity is the difficulty or challenge of the training program. It would be valuable to know if high-intensity RBT improves balance reactions quickly. The main goal of this study is to see if more intense RBT improves balance reactions faster than less intense RBT. The investigators will compare how quickly people improve balance reactions between high- and moderate-intensity RBT, and between RBT and a control program that does not include RBT. The investigators will also test if the improvements in balance reactions last after the training program is over. The secondary goals are to understand exactly how balance reactions improve with training, and to determine if people who complete RBT improve their general balance skills, and falls efficacy more than people who do not complete RBT.

Participants needed: 96
Trial details
Age: 65-80Biological sex: AllType: InterventionalSponsor: Toronto Rehabilitation InstituteUpdated: Jan 27, 2025Locations: 1
Eligibility criteria

Community-dwelling older adults (65-80 years old)

Unable to stand independently without upper-limb support for >30 seconds and/or... [+6]

Status: Recruiting

Optimal Intensity of Reactive Balance Training Post-stroke

Falls in daily life are a serious risk for people with stroke. A new type of balance training, called reactive balance training (RBT). may help to reduce this risk of falling. In some previous studies participants improved their balance reactions a lot after RBT, whereas others did not improve at all. These studies used different types and amounts of training. Differences in training program features might explain differences in the study results. Training intensity is the difficulty or challenge of the training program. For other types of exercise (like 'cardio' or strength training) if the intensity of exercise is increased, someone can get the same benefits in less time than with lower intensity exercise. Physiotherapists report that they have limited time in rehabilitation to do everything they need to do with their stroke patients, so it would be valuable to know if high-intensity RBT improves balance reactions quickly. The goal of this study is to see if more intense RBT improves balance reactions faster than less intense RBT. People with chronic stroke will be randomly placed in one of three groups: high-intensity RBT, moderate-intensity RBT, or a walking control group. The investigators will find the fastest moving platform speed that participants can respond to with single step (multi-step threshold). There will then be 4 1-hour long training sessions in one week. Participants in the high-intensity group will experience platform movements that are 50% faster than the multi-step threshold. Participants in the moderate-intensity group will experience platform movements at the multi-step threshold. Participants in both RBT groups will experience 36 multi-directional platform movements in each training session, causing them to start to fall forwards, to the left, or to the right. Participants in the walking group will walk on the platform 36 times without any platform movements. The investigators will measure how quickly people improve their balance reactions over the training program.

Participants needed: 63
Trial details
Age: 20+Biological sex: AllType: InterventionalSponsor: Toronto Rehabilitation InstituteUpdated: Jan 27, 2025Locations: 1
Eligibility criteria

Chronic stroke (>6 months post-stroke)

Are unable to stand independently without upper-limb support for >30 seconds and... [+4]

Status: Recruiting

Self-Management Interventions for Long COVID-19

The purpose of this study is to investigate and compare the feasibility and efficacy of two group-based interventions (education vs. mindfulness) to help self-manage Long-COVID symptoms.

Participants needed: 270
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Toronto Rehabilitation InstituteUpdated: Nov 25, 2024Locations: 1
Eligibility criteria

Clinically diagnosed Long-COVID plus PCR positivity with and without hospitaliza... [+5]

Acute ventilator support [+3]

Status: Recruiting

Online Memory Intervention for Individuals with Traumatic Brain Injury

This study will examine the behavioural and neurophysiological efficacy and feasibility of an online spatial navigation intervention for improving memory and brain health in individuals who have sustained moderate-severe traumatic brain injury.

Participants needed: 84
Trial details
Age: 18-55Biological sex: AllType: InterventionalSponsor: Toronto Rehabilitation InstituteUpdated: Nov 25, 2024Locations: 1
Eligibility criteria

acute care diagnosis of m-sTBI [+6]

neurological disorder other than TBI (e.g., dementia, stroke) [+5]