Status: Recruiting
Phase 1b, Open-label Study of Tune-401 to Assess Safety, PK and PD in Adults With Chronic Hepatitis B
This study will be conducted to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of Tune-401 in adult participants with Chronic Hepatitis B.
Participants needed: 36
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Tune Therapeutics, Inc.Updated: Jan 6, 2026Locations: 3
Eligibility criteria
M/F, BMI ≥ 18.5 kg/m² at screening, age 18-75, inclusive [+3]
ALT/ AST ≥ 1.5 × upper limit of normal (ULN) and total bilirubin ≥ 1. 5 × ULN [+2]