Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Which Rapid Sequence Induction Technique Should be Used in Urgent Surgery in Children?

The goal of our study is to compare classical Rapid Sequence Induction (RSI) and modified Rapid Sequence Induction (mRSI) in pediatric patients with a full stomach undergoing urgent surgical procedures. Due to reduced oxygen reserve in children, modified RSI incorporating gentle positive pressure ventilation has been proposed to reduce hypoxemia while maintaining protection against aspiration.

Participants needed: 100
Trial details
Age: 1-14Biological sex: AllType: InterventionalSponsor: Tunis UniversityUpdated: Feb 23, 2026Locations: 1
Eligibility criteria

children under 14 years of age with a full stomach, scheduled for urgent surgery...

hemodynamic instability

Status: Recruiting

Early Administration of Norepinephrine in Sepsis

The management of septic states includes, in addition to the specific treatment (antimicrobials and eradication of the source), a restoration of the hemodynamic disorders and assistance of the failing organs. In general, the restoration of hemodynamic disorders begins first with volume expansion, followed by the use of Noepinephrine (NE) when the target mean arterial pressure (MAP) is not reached after optimizing the intravascular volume. Recently, several studies have supported the interest of early NE on MAP, cardiac output and mortality. It is therefore tempting to restrict fluid administration even in the initial phase of hemodynamic management of severe sepsis by starting NE earlier.

Participants needed: 200
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Tunis UniversityUpdated: Dec 4, 2024Locations: 1
Eligibility criteria

Age 18 or older. [+3]

Diagnosis of septic shock prior to randomization (where NA requirements exceed t... [+5]

Status: Recruiting

Management of Preoperative Anxiety in Children: Could a Lollipop Be the Solution?

The aim of the study is to evaluate the effectiveness of distraction using a lollipop versus premedication with intranasal midazolam to manage preoperative anxiety in pediatric anesthesia.

Participants needed: 63
Trial details
Age: 4-10Biological sex: AllType: InterventionalSponsor: Tunis UniversityUpdated: Nov 1, 2024Locations: 1
Eligibility criteria

Age > 4 ans , ASA 1 ou 2

Children who rejected premedication - The occurrence of perioperative complicati...

Status: Recruiting

Orotracheal Intubation in Newborns: Videolaryngoscopy Vs Direct Laryngoscopy

The children were randomized into two groups to receive orotracheal intubation after anesthetic induction with neuromuscular blockade, either by direct laryngoscopy (DL, DL group) or by C-MAC video laryngoscopy (VL group)

Participants needed: 115
Trial details
Age: 1-30Biological sex: AllType: InterventionalSponsor: Tunis UniversityUpdated: Oct 23, 2024Locations: 1
Eligibility criteria

newborns requiring orotracheal intubation for surgery or mechanical ventilation...

age> 01 month

Status: Recruiting

What Technique for Caudal Block in Children: Conventional or Ultrasound-guided

The goal of our study is to compare ultrasound-guided caudal block to the conventional technique based on anatomical landmarks.

Participants needed: 94
Trial details
Age: 6-6Biological sex: AllType: InterventionalSponsor: Tunis UniversityUpdated: Oct 23, 2024Locations: 1
Eligibility criteria

children aged between 6 months and 6 years, ASA 1 , underwent elective surgery

severe systemic diseases, previous neurological or spinal disorders, coagulation...