Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

The main goals of this clinical study are to learn if AMT-260 is safe and tolerable and works to reduce the frequency of seizures in adults with unilateral mesial temporal lobe epilepsy (MTLE).

Participants needed: 12
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: UniQure Biopharma B.V.Updated: Jun 2, 2026Locations: 18
Eligibility criteria

Diagnosis of unilateral refractory MTLE [+6]

Implanted devices that would contraindicate MRI; MRI-compatible devices must be... [+7]

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Status: Recruiting

Safety, PK/PD, and Exploratory Efficacy Study of AMT-191 in Classic Fabry Disease

The main goals of this clinical study are to characterize safety and PK/PD of AMT-191 i.e. if drug doses used in the study are safe and tolerable and to understand how it acts in the body of people with Fabry disease.

Participants needed: 12
Trial details
Phase: Phase 1, Phase 2Age: 18-50Biological sex: MaleType: InterventionalSponsor: UniQure Biopharma B.V.Updated: Oct 23, 2025Locations: 8
Eligibility criteria

Male of age ≥ 18 years and ≤50 years [+6]

Any allergic hypersensitivity reaction to ERT or infusion reaction in the 12 mon... [+22]

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