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Condition / disease
Location
Status: Not yet recruiting

Effect of Enamel Cleaning on a Remineralizing Paste for Hypomineralizated Lesions

Molar-incisor hypomineralization (MIH) is a qualitative defect of dental enamel, in which low mineral content and high protein content compromise the effectiveness of remineralizing treatments. Various agents have been used to remove proteins from hypomineralized enamel, such as sodium hypochlorite (NaOCl). Sodium hypochlorite is an antimicrobial irrigant capable of dissolving tissues. CPP-ACPF is used as a remineralizing agent for MIH lesions, it is capable of stabilizing calcium, phosphate, and fluoride ions on the tooth surface, maintaining them in an amorphous form. Therefore, the objective of this study is to evaluate the clinical performance of amorphous calcium fluoride casein phosphate phosphopeptide (CPP-ACPF) dental mousse on deproteinized hypomineralized enamel.

Participants needed: 54
Trial details
Age: 7-9Biological sex: AllType: InterventionalSponsor: Universidade CeumaUpdated: Jun 17, 2026Locations: 1
Eligibility criteria

Children must have at least one permanent molar without MIH, at least two perman...

Children with visible bacterial biofilm, enamel malformations associated with sy...