Clinical trials

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Condition / disease
Location
Status: Recruiting

Oxytocin and Fetal Heart Rate Changes

The reported risk of nonreassuring fetal heart trace following neuraxial analgesia is 3-23%. This variability may be due to fluid and oxytocin management prior to and during the initiation of neuraxial analgesia. The study hypothesis is that decreasing the oxytocin infusion rate by 50 % prior to initiation of combined spinal epidural analgesia will cause a reduction in the incidence of adverse fetal heart rate changes.

Participants needed: 730
Trial details
Phase: Phase 4Age: 18-55Biological sex: FemaleType: InterventionalSponsor: Unyime ItukUpdated: Jun 4, 2025Locations: 2
Eligibility criteria

Healthy nulliparous or multiparous women at term (37 > weeks' gestation) [+3]

Use of chronic analgesic medications [+4]