Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Donepezil and Cognitive Training for Alcohol Use Disorder (AUD)

The goal of the project is to evaluate whether donepezil + cognitive remediation therapy is superior to placebo in reducing heavy drinking in patients with alcohol use disorder in a double-blind, placebo-controlled trial.

Participants needed: 160
Trial details
Phase: Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: VA Connecticut Healthcare SystemUpdated: Jun 23, 2026Locations: 1
Eligibility criteria

Males and females 18-80 years of age [+5]

Lifetime diagnosis of a psychotic disorder, not induced by drug use [+12]

Status: Recruiting

Building an Equitable and Accessible System of Eating Disorder Care for VA, DoD, and Underrepresented Americans

When untreated, eating disorders present with tremendous burdens to affected active duty Service members and Veterans and their families, and are very costly to the DoD and VA healthcare system. A comparative effectiveness study with state-of-the-art virtual treatment for BN and BED specifically adapted for testing with the Veteran population and other underrepresented eating disorder populations will lead to major improvements in clinical outcomes. The treatment will be integrated with VA's newest telehealth technology to profoundly enhance access to care anywhere, at any time. This trial of therapist-led and self-help CBT treatments, combined with our expert panel methods to inform VA Clinical Practice Guidelines for Eating Disorders and plans for dissemination, will accelerate the pace for the transition of results both for large-scale deployment in the VA system and for real-world impact among diverse and underrepresented eating disorder populations.

Participants needed: 144
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: VA Connecticut Healthcare SystemUpdated: Nov 25, 2025Locations: 1
Eligibility criteria

Aged 18 and older [+2]

Active psychosis or high acute risk for suicide [+3]

Status: Recruiting

Intranasal Insulin for Posttraumatic Stress Disorder

To evaluate if intranasal insulin is effective in reducing PTSD symptoms.

Participants needed: 20
Trial details
Phase: Phase 2Age: 21-65Biological sex: AllType: InterventionalSponsor: VA Connecticut Healthcare SystemUpdated: Sep 16, 2025Locations: 1
Eligibility criteria

Male or female, 21-65 years old [+2]

Unstable medical condition, clinically determined by a physician [+10]