Clinical trials

2

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Condition / disease
Location
Status: Recruiting

Study to Evaluate Subcutaneous (SC) VGA039 in Patients With Von Willebrand Disease (VWD)

This is a phase 3 study that will evaluate subcutaneous (SC) VGA039 in patients with von Willebrand Disease (VWD)

Participants needed: 60
Trial details
Phase: Phase 3Age: 12-75Biological sex: AllType: InterventionalSponsor: Vega Therapeutics, IncUpdated: Apr 3, 2026Locations: 14
Eligibility criteria

12 to 75 years of age, inclusive [+5]

Use of routine prophylaxis of VWF-containing concentrates defined as at least 1... [+5]

Status: Recruiting

Study of VGA039 in Healthy Volunteers and Patients With Von Willebrand Disease (VIVID)

The VIVID study is structured in a master protocol format comprised of multiple parts that evaluate intravenous (IV) and subcutaneous (SC) VGA039 in healthy volunteers and subjects with von Willebrand Disease (VWD) and other bleeding disorders.

Participants needed: 116
Trial details
Phase: Phase 1, Phase 2Age: 12-60Biological sex: AllType: InterventionalSponsor: Vega Therapeutics, IncUpdated: Aug 26, 2025Locations: 25
Eligibility criteria

Subjects, 18 to 60 years of age, inclusive for Parts 1 and 2 [+9]

Baseline FVIII activity > 50 IU/dL. [+1]