Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee

The objective of this study is to compare the efficacy and safety of MACI® vs arthroscopic microfracture in the treatment of participants aged 10 to 17 years with symptomatic articular chondral or osteochondral defects of the knee.

Participants needed: 45
Trial details
Phase: Phase 3Age: 10-17Biological sex: AllType: InterventionalSponsor: Vericel CorporationUpdated: Jun 24, 2026Locations: 12
Eligibility criteria

Symptomatic cartilage or osteochondral defects [+3]

At least 1 defect size ≥1.5 cm2 on the patella, femoral condyles and/or the troc... [+21]

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Status: Recruiting

A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle

The objective of this study is to demonstrate the superiority of MACI (autologous cultured chondrocytes on porcine collagen membrane) versus Bone Marrow Stimulation in the treatment of patients aged 17 to 65 years with symptomatic articular chondral or osteochondral defects of the talus.

Participants needed: 309
Trial details
Phase: Phase 3Age: 17-65Biological sex: AllType: InterventionalSponsor: Vericel CorporationUpdated: May 27, 2026Locations: 4
Eligibility criteria

Age 17 to 65 at the time of planned randomization visit (Visit 2). [+7]

Lesions with an underlying bony defect depth of > 5 mm. [+19]

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