Status: Recruiting
A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer
This is a first-in-human phase I/II study to examine the safety, tolerability and preliminary efficacy of VLS-1488 in subjects with advanced cancers.
Participants needed: 200
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Volastra Therapeutics, Inc.Updated: Nov 4, 2025Locations: 14
Eligibility criteria
All Parts: Age ≥ 18 years, ECOG Performance Status ≤ 1, at least 1 site of measu... [+2]
MSI-H, dMMR, POLE gene hotspot mutated, or known hypermutator phenotype [+6]