Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study to Evaluate Safety and Efficacy of WSD0922-FU Combo With Osimertinib for NSCLC

This is a Phase I/II, Open Label Study of WSD0922-FU in Combination with Osimertinib for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer whose disease has progressed with third-generation EGFR-TKI with C797S mutation or is newly diagnosed with CNS metastasis with EGFR Del19 or L858R mutation

Participants needed: 48
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Wayshine Biopharm, Inc.Updated: Nov 28, 2025Locations: 1
Eligibility criteria

≥Age 18, gender is not limited; [+9]

Received chemotherapy, radiotherapy, biological therapy, targeted therapy, endoc... [+16]

Status: Recruiting

A Study to Assess the Efficacy of WSD0922-FU in Patients With C797S+ Advanced Non-small Cell Lung Cancer

This is a Phase II, Open Label, Multicenter, Single Arm Study of WSD0922-FU for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer whose Disease has Progressed with First-Line Osimertinib Treatment and whose Tumors harbor a C797S mutation within the Epidermal Growth Factor Receptor Gene.

Participants needed: 40
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Wayshine Biopharm, Inc.Updated: Sep 8, 2025Locations: 18
Eligibility criteria

Provision of signed and dated, written informed consent prior to any study-speci... [+8]

Any investigational agents or other anticancer drugs from a previous treatment r... [+9]

Status: Recruiting

A Study to Assess the Efficacy and Safety of WSD0922-FU in Patients With EGFRm+ Advanced Non-small Cell Lung Cancer

This study is a multicenter, open label, single-arm phase I/II clinical trial of WSD0922-FU for patients with locally advanced or metastatic non-small cell lung cancer whose disease has progressed with thrid-generation EGFR-TKI .

Participants needed: 100
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Wayshine Biopharm, Inc.Updated: Aug 29, 2025Locations: 12
Eligibility criteria

Age 18-75 years old (including the threshold value), gender is not limited; [+9]

Received chemotherapy, radiotherapy, biological therapy, targeted therapy, endoc... [+20]