Clinical trials

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Condition / disease
Location
Status: Recruiting

A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius)

This study is trying to identify the right dose of a long-acting medicine called WIN378 for people with moderate - severe chronic obstructive pulmonary disease (COPD). WIN378 blocks the action of a protein called TSLP that causes inflammation in the lung and may contribute to COPD control and symptoms. The study will test how doses of WIN378 are handled by the body (pharmacokinetics) and assess the safety of the medicine and markers of COPD inflammation in exhaled breath and blood, lung function and COPD control (pharmacodynamics)

Participants needed: 105
Trial details
Phase: Phase 2Age: 40-80Biological sex: AllType: InterventionalSponsor: Windward BioUpdated: Jun 22, 2026Locations: 4
Eligibility criteria

Adults aged 40 to 80 years [+5]

Clinically significant pulmonary disease other than chronic obstructive pulmonar... [+7]