Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Pre- and Post-neuromusculoskeletal Injury Risk Evaluation for Return-to-Duty Enhancement

The purpose of this study is to develop comprehensive and efficient pre- and post- musculoskeletal injury (MSKI) risk assessments for Service members, incorporating both objective and subjective measures. This is a multi-site observational study to identify the pre- and post-MSKI physical and psychosocial factors contributing to MSKI risks and undesired patient outcomes following MSKI. The study hypothesis is that a set of field-expedient clinical assessments can identify Service member specific MSKI risk factors and post-MSKI deficits that contribute to undesired patient outcomes and provide data to guide patient-specific risk mitigation and rehabilitation programs.

Participants needed: 2,690
Trial details
Age: 18-44Biological sex: AllType: ObservationalSponsor: Womack Army Medical CenterUpdated: Jun 3, 2026Locations: 2
Eligibility criteria

Active duty Service members cleared for full physical activity. [+6]

Currently on limited duty status, for any reason. [+11]

Status: Recruiting

Neurocognitive Ankle Training for Instability to Optimize Neuromusculoskeletal Outcomes (NATION)

The purpose of this study is to examine the effectiveness of a novel ankle rehabilitation protocol on improving clinical and health outcomes in physically active individuals with chronic ankle instability (CAI). Our central hypothesis is NATION, a novel rehabilitation intervention that includes neurocognitive tasks, will improve overall health and function, and reduce lower extremity musculoskeletal injury in physically active individuals with CAI.

Participants needed: 180
Trial details
Age: 18-44Biological sex: AllType: InterventionalSponsor: Womack Army Medical CenterUpdated: Apr 22, 2026Locations: 2
Eligibility criteria

Physically active and engage in regular exercise/training [+7]

Unable to read or comprehend the English language. [+5]

Status: Recruiting

Emovi 3D Knee Assessment Device Intervention for Operational Readiness

This is a randomized clinical trial investigating the use of the Emovi Knee Kinesiography information in the treatment of anterior knee pain in physical therapy.

Participants needed: 180
Trial details
Age: 18-50Biological sex: AllType: InterventionalSponsor: Womack Army Medical CenterUpdated: Jul 16, 2025Locations: 2
Eligibility criteria

Age 18-50 [+2]

Pregnancy [+5]

Status: Not yet recruiting

Assessment of Myocarditis After Replication-Deficient Smallpox Immunization

This is a prospective observational phase IV study of a novel, replication-deficient smallpox vaccine that has been recently been approved by FDA. The purpose of this study is to determine if there are any abnormalities detected by electrocardiographic testing and/or blood tests within 35 days of receiving the second dose of smallpox vaccine either alone or co-administered with other vaccines that may/may not be suggestive of myopericarditis.

Participants needed: 2,350
Trial details
Age: 18-45Biological sex: AllType: ObservationalSponsor: Womack Army Medical CenterUpdated: Dec 14, 2023
Eligibility criteria

Active duty military personnel within the range of 18-45 years of age without li... [+2]

Known contraindication to replication deficient smallpox vaccination based on FD... [+7]