Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

HWS116 Monotherapy in Patients With Advanced Solid Tumors

This is a Phase I open-label study that will evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of HWS116 monotherapy in patients with advanced solid tumors.

Participants needed: 56
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Wuhan Humanwell Innovative Drug Research and Development Center Limited CompanyUpdated: Apr 28, 2026Locations: 1
Eligibility criteria

Aged ≥18 years at the time of signing the Informed Consent Form (ICF); [+7]

Known allergy to the investigational product, drugs of the same class, or any ex... [+15]

Status: Recruiting

A Phase I Study of HW201877 in Healthy Subjects

This is a Phase I, randomized, double-blind, placebo-controlled study to assess the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD), and food effect (FE) of HW201877 in healthy subjects following (1) a single ascending dose (Part 1), which includes a single-dose, two-period crossover FE cohort; (2) a multiple ascending dose (Part 2).

Participants needed: 104
Trial details
Phase: Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Wuhan Humanwell Innovative Drug Research and Development Center Limited CompanyUpdated: Jan 28, 2026Locations: 1
Eligibility criteria

Before enrollment in the study, each subject shall sign the informed consent for... [+3]

Smoking more than 5 cigarettes per day within 3 months prior to screening. [+8]

Status: Recruiting

HW071021 Monotherapy in Patients With Advanced Solid Tumors

This is a Phase I open-label study that will evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of HW071021 monotherapy in patients with advanced solid tumors.

Participants needed: 76
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Wuhan Humanwell Innovative Drug Research and Development Center Limited CompanyUpdated: Dec 29, 2025Locations: 1
Eligibility criteria

Age of 18 years or older, applicable to both males and females. [+8]

Known allergy to the investigational drug, drugs with the same mechanism of acti... [+18]