Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Machine Learning-based Classification of Symptom Clusters and Online CBT

To breakthrough the bottleneck identified, we will conduct a cross-sectional study to develop a symptom clustering model for depression and anxiety. A wide range of statistical methods as well as machine learning approaches were explored, and a cohesive hierarchical clustering algorithm will be used. After developing the model, a symptom-matched intervention program based on problem solving therapy will be formulated. We are supposed to examine whether its use for personalizing symptom-matched psychological treatment can lead to improved patient outcomes, compared with usual care. This project is expected to provide a new and precise method for the emotion management, which will provide a standardized intervention pathway combining screening with treatment for the management of depression symptom and anxiety symptom. A preciser intervention matched to individual symptoms may provide important insight in improving patient outcome as well as a standardized mood management pathway targeting to the early detection and intervention for community residents.

Participants needed: 380
Trial details
Age: 18-64Biological sex: AllType: InterventionalSponsor: Wuhan Mental Health CentreUpdated: May 12, 2026Locations: 1
Eligibility criteria

Aged between 18 and 64 years. PHQ-9 ≥10 and/or GAD-7 ≥8 at baseline assessment d...

They are receiving psychological therapy during an interview for any mental heal... [+2]

Status: Not yet recruiting

Multimodal Identification of Depressive Symptoms in the Elderly

Screening with depression scales alone is subjective, and relying on single-modal data often leads to incomplete identification of symptoms that are easily missed or misdiagnosed. In this study, we first aim to use artificial intelligence to construct a depression symptom recognition model, concatenate multimodal features such as facial expression, audio, text, and postural behavior, and deeply fuse them to construct a multimodal model.

Participants needed: 2,000
Trial details
Age: 60-100Biological sex: AllType: ObservationalSponsor: Wuhan Mental Health CentreUpdated: Aug 11, 2025Locations: 1
Eligibility criteria

Elderly individuals aged 60 years or older. [+3]

Those who meet the diagnostic criteria for cognitive impairment (dementia) as st... [+2]

Status: Not yet recruiting

Home-Based Executive Function Training Intervention For Attention-Deficit/ Hyperactivity Disorder-prone Children

This study aims to investigate the effectiveness of a home-based executive function training Intervention on children's ADHD symptoms, executive function and parents' parenting stress.

Participants needed: 100
Trial details
Age: 6-12Biological sex: AllType: InterventionalSponsor: Wuhan Mental Health CentreUpdated: Apr 30, 2025
Eligibility criteria

1.SNAP-IV scale, inattention or hyperactivity-impulsivity scale score > 1.2 [+3]

1.Children or parents with severe organic encephalopathy and other severe mental... [+2]