Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

BPI-361175 Tablets in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

This is a three-stage study, consisting of Phase Ia dose-escalation, Phase Ib dose expansion, and a Phase II component.

Participants needed: 30
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Xcovery Holdings, Inc.Updated: Oct 7, 2025
Eligibility criteria

Male or female ≥ 18 years old; [+13]

Presence of another active primary malignant tumors; [+12]

Status: Available

Expanded Access to Ensartinib for Participants With ALK+ NSCLC

This is an open-label, multicenter, intermediate-sized expanded access treatment protocol to the existing IND 111,695 for ensartinib (X-396). The treatment plan is designed to provide ensartinib to participants with anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC).

Trial details
Age: 18+Biological sex: AllType: Expanded AccessSponsor: Xcovery Holdings, Inc.Updated: Oct 20, 2022Locations: 4
Eligibility criteria

Adult patients (>18 years-of-age) with advanced ALK-positive NSCLC as determined... [+7]

Patients currently receiving cancer therapy. [+11]