Health Trials

Clinical trials

2

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Condition / disease
Location
Status: Recruiting

Polyspecific Antibodies in Lymphoproliferative T-cell Disorders

This is a 2-part study consisting of a Part 1, dose escalation and dose-finding component to establish the Maximal Tolerated Dose (MTD), or Recommended Part 2 Dose (RP2D) of LIS1 as a single agent; followed by a Part 2, to investigate anti-tumors efficacy of LIS1 in selected subtypes of Peripheral TCell Lymphoma (PTCL) and to further evaluate its safety and tolerability at RP2D.

Participants needed: 54
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Xenothera SASUpdated: Jul 22, 2025Locations: 8
Eligibility criteria

Provide signed, written informed consent. [+23]

Is diagnosed with a bulky disease (≥10 cm). [+40]

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Status: Recruiting

FIH XON7 in Advanced/Metastatic Solid Tumors

This is a two-stage trial consisting of a Part I, dose escalation and dose-finding component to establish the Maximal Tolerated Dose (MTD), if any, and Recommended Part 2 Dose (RP2D) of XON7, followed by a Part II component to investigate anti-tumors efficacy in selected solid tumor types and to further evaluate safety and tolerability of XON7 at RP2D.

Participants needed: 255
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Xenothera SASUpdated: Jun 22, 2025Locations: 5
Eligibility criteria

Provide signed, written informed consent. [+14]

A participant who has received more than 4 prior lines of therapy for advanced o... [+28]

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