Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Prospective Cohort Study of Neuromyelitis Optica Spectrum Disorders (NMOSD)

This study aims to characterize sex hormone alterations and their potential clinical significance in NMOSD patients from Southern China through comprehensive hormonal profiling.

Participants needed: 4,000
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Xiamen Hospital of Traditional Chinese MedicineUpdated: Dec 18, 2025Locations: 5
Eligibility criteria

Aged 18 years or older, regardless of sex [+6]

Diagnosis of other serious systemic diseases (e.g., malignancy) [+6]

Status: Not yet recruiting

Effects of Peginterferon Consolidation Therapy on Hepatic cccDNA Dynamics in CHB Patients Achieving Clinical Cure.

This is a single-center, prospective, exploratory clinical study. The study plans to enroll 30 chronic hepatitis B (CHB) patients which achieved HBsAg clearance based peginterferon α-2b treatment. Eligible subjects will receive either 12-24 weeks interferon consolidation therapy (180μg administered subcutaneously in the abdomen or thigh once weekly) or not according to physician's recommendation and patient's preference, with regular follow-up for HBV recurrence. Patients will be followed up every 12 weeks. The study will evaluate changes in intrahepatic covalently closed circular DNA (cccDNA) and peripheral blood HBV pregenomic RNA (pgRNA) levels after achieving HBsAg clearance.

Participants needed: 30
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Xiamen Hospital of Traditional Chinese MedicineUpdated: Apr 9, 2025Locations: 1
Eligibility criteria

Voluntarily enroll in the study, able to understand and voluntarily sign the inf... [+5]

Lactating women; [+5]