Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Real-World Study of Guselkumab in Chinese Participants With Ulcerative Colitis

The purpose of this study is to assess the measurable changes in health, function, or quality of life (clinical outcomes) after receiving guselkumab in real-world clinical practice amongst Chinese participants with ulcerative colitis (UC; a long-term disease of the large intestine in which the lining of the colon \[part of large intestine\] becomes inflamed and develops tiny open ulcers), who have not received biologic therapy (a medicine made from living organisms or their components) previously.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Xian-Janssen Pharmaceutical Ltd.Updated: Jun 5, 2026Locations: 9
Eligibility criteria

Has a confirmed diagnosis of moderately to severely active UC, defined as: a) ba... [+3]

Acute severe UC or infectious colitis or other conditions when patients is likel... [+4]

Status: Recruiting

A Study to Evaluate the Efficacy of Guselkumab in Chinese Participants With Crohn's Disease (CD)

The purpose of this study is to evaluate how well guselkumab works in participants with Crohn's disease (CD; a long-term condition causing severe inflammation of the intestinal tract) who no longer respond to treatment with ustekinumab.

Participants needed: 78
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Xian-Janssen Pharmaceutical Ltd.Updated: Jun 5, 2026Locations: 5
Eligibility criteria

Has a confirmed diagnosis of Crohn's disease (CD) [+4]

Have responded well to treatment with UST in a dosing regime that is not in line... [+4]