Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical Hyperplasia

To investigate the efficacy of weight management plus levonorgestrel intrauterine system (LNG-IUS) or megestrol acetate (MA) in obese patients with endometrial atypical hyperplasia (EAH) asking for conservative therapy.

Participants needed: 172
Trial details
Phase: Phase 2, Phase 3Age: 18-45Biological sex: FemaleType: InterventionalSponsor: Xiaojun ChenUpdated: Jun 4, 2026Locations: 1
Eligibility criteria

Combined with severe medical disease or liver or kidney dysfunction: alanine ami... [+13]

Status: Recruiting

GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients

To investigate the efficacy of GnRHa plus letrozole in obese progestin-insensitive EEC patients.

Participants needed: 29
Trial details
Phase: Phase 2, Phase 3Age: 18-45Biological sex: FemaleType: InterventionalSponsor: Xiaojun ChenUpdated: Aug 11, 2025Locations: 2
Eligibility criteria

Have a confirmed initial pathological diagnosis based upon hysteroscopy: histolo... [+9]

Combined with severe medical disease or severely impaired liver and kidney funct... [+7]

Status: Recruiting

GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients

To investigate the efficacy of GnRHa plus letrozole vs Diane-35 plus metformin in non-obese progestin-insensitive early-stage endometrial cancer (EEC) and atypical hyperplasia(EAH) patients asking for conservative treatment.

Participants needed: 80
Trial details
Phase: Phase 2, Phase 3Age: 18-45Biological sex: FemaleType: InterventionalSponsor: Xiaojun ChenUpdated: Aug 11, 2025Locations: 2
Eligibility criteria

Have a confirmed initial pathological diagnosis based upon hysteroscopy: histolo... [+9]

Combined with severe medical disease or severely impaired liver and kidney funct... [+7]