Clinical trials

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Condition / disease
Location
Status: Not yet recruiting

Adebrelimab Plus S-1 for Resected Cholangiocarcinoma

The goal of this clinical trial is to learn whether adebrelimab combined with S-1 works as an adjuvant treatment for patients with cholangiocarcinoma after curative surgery. It will also learn about the safety of this treatment. The main questions it aims to answer are: * Does adebrelimab combined with S-1 reduce the risk of cancer recurrence after surgery? * What side effects do participants experience when receiving this treatment? All participants in this study will receive adebrelimab combined with S-1. There is no comparison group in this study. Participants will: * Receive adebrelimab by intravenous infusion once every 3 weeks for 4 cycles * Take S-1 by mouth twice daily for 4 weeks, followed by a 2-week rest, for 4 cycles * Visit the hospital regularly for checkups, laboratory tests, and imaging examinations (CT or MRI) * Be followed up for safety and survival after completing treatment

Participants needed: 40
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Xingjun GuoUpdated: May 1, 2026
Eligibility criteria

Histologically or pathologically confirmed malignant cholangiocarcinoma. [+7]

Prior treatment with immune checkpoint inhibitors or other agents targeting T-ce... [+10]