Status: Recruiting
Efficacy and Safety of 14-Day Vonoprazan-Based Dual Therapy Versus Quadruple Therapy for Helicobacter Pylori Eradication: A Multicentre, Non-Inferiority Randomized Controlled Trial
This study is a multicentre, non-inferiority randomized controlled trial to compare the efficacy and safety of 14-day vonoprazan-based dual therapy with versus quadruple therapy for the eradication of Helicobacter pylori. The primary outcome is eradication rate, and the secondary outcome includes the incidence of adverse events and compliance.
Participants needed: 372
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Yanqing LiUpdated: Apr 15, 2026Locations: 2
Eligibility criteria
Aged 18-70 years, male or female [+2]
Severe underlying conditions, such as hepatic insufficiency, renal insufficiency... [+7]