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Condition / disease
Location
Status: Recruiting

Targeted Temperature Management Via Bladder Monitoring in ICH

The goal of this clinical trial is to learn whether a bladder temperature monitoring-guided targeted temperature management (TTM) strategy improves functional recovery in patients with severe intracerebral hemorrhage, compared to conventional temperature monitoring. It will also assess the safety of this monitoring approach. The main questions it aims to answer are: * Does continuous bladder temperature monitoring-guided TTM improve the likelihood of a favorable functional outcome (modified Rankin Scale score 0-2) at 180 days after onset? * What medical problems (such as infections, shivering, deep vein thrombosis, or sepsis) do participants experience while under the TTM strategy? Researchers will compare the intervention group (using continuous bladder temperature monitoring) with the control group (using conventional intermittent temperature monitoring with a mercury thermometer at the armpit) to see if the bladder temperature-guided TTM strategy leads to better outcomes. Participants will: * Be randomly assigned to one of the two temperature monitoring strategies * Receive standard medical and surgical care for severe intracerebral hemorrhage

Participants needed: 318
Trial details
Age: 18-85Biological sex: AllType: InterventionalSponsor: Yanyan GongUpdated: Jun 10, 2026Locations: 1
Eligibility criteria

Neurocritical care patients: Study subjects are patients with first-time spontan... [+5]

Fever (≥38.0°C) that lasted over 1 hour or occurred more than once prior to enro... [+7]