Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy and Durability of a Personalized Treat-and-extend Regimen of Faricimab for Treatment-naive Polypoidal Choroidal Vasculopathy

To evaluate the Efficacy of a personalized treat-and-extend regimen of faricimab for treatment-naive polypoidal choroidal vasculopathy

Participants needed: 50
Trial details
Phase: Phase 3Age: 50+Biological sex: AllType: InterventionalSponsor: Yeungnam University College of MedicineUpdated: Mar 10, 2026Locations: 1
Eligibility criteria

Presence of active polypoidal lesions in the macula as shown by Indocyanine gree... [+6]

Previous treatment with any anti-VEGF drugs or faricimab or investigational drug... [+22]

Status: Recruiting

Prospective Trial of the Efficacy and Safety of a Personalized Regimen of High-dose Aflibercept 8mg on Treatment-naive Polypoidal Choroidal Vasculopathy: the PALLAS Trial

The purpose of this study is to evaluate the efficacy and safety of the aflibercept 8 mg used in a personalized regimen, with flexible loading dose and treatment intervals from 8 to 24 weeks in eyes with treatment-naive PCV.

Participants needed: 50
Trial details
Phase: Phase 3Age: 19+Biological sex: AllType: InterventionalSponsor: Yeungnam University College of MedicineUpdated: Feb 5, 2026Locations: 1
Eligibility criteria

Signed informed consent must be obtained prior to participation in the study. [+3]

Ocular conditions/disorders at screening or baseline which could, in the opinion... [+7]