Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of EH002 Gene Therapy for Otoferlin Gene Mutation-mediated Hearing Loss

The study is designed to evaluate the safety, tolerability, and preliminary efficacy of EH002 for the treatment of congenital deafness caused by mutations in the OTOF gene. Participants may receive one or two injections of the EH002 gene therapy in one or both ears.

Participants needed: 24
Trial details
Age: 6+Biological sex: AllType: InterventionalSponsor: Yilai ShuUpdated: Jul 25, 2025Locations: 2
Eligibility criteria

The participant and/or their legal guardian must provide informed consent before... [+6]

The genetic diagnosis does not indicate an OTOF mutation. [+14]

Status: Not yet recruiting

A Clinical Trial of the Safety and Efficacy of TJ0113 Capsules in the Treatment of Patients With Age-related Hearing Loss

The purpose of this study is to explore the safety and efficacy of TJ0113 capsules in patients with age-related hearing loss.

Participants needed: 60
Trial details
Age: 65-75Biological sex: AllType: InterventionalSponsor: Yilai ShuUpdated: Jun 10, 2025Locations: 1
Eligibility criteria

The subjects voluntarily participate in the clinical trial, sign the informed co... [+4]

The presence of implants in the study ear (such as cochlear implant, artificial... [+6]