Clinical trials

7

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Phase 1 Study to Evaluate Pharmacokinetics, Safety and Tolerability of ZL-1503 in Healthy Volunteers

This is a phase 1, single dose, randomized, open-label, parallel-group study to evaluate the pharmacokinetics (PK), safety, tolerability and immunogenicity of ZL-1503 and to explore its PD biomarkers following a single subcutaneous (SC) or intravenous (IV) administration in healthy volunteers.

Participants needed: 36
Trial details
Phase: Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Jun 22, 2026Locations: 1
Eligibility criteria

Healthy male and female volunteers, 18-65 years of age [+2]

Significant health issues, such as positive tests for human immunodeficiency vir... [+6]

Status: Recruiting

Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors

The purpose of this study is to evaluate the safety and tolerability of investigational study drug ZL-6201 for treating sarcoma and solid tumors cancer.

Participants needed: 180
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Jun 22, 2026Locations: 6
Eligibility criteria

Adult men and women ≥18 years of age at the time of signing the ICF with an East... [+7]

Participants with another known malignancy that has required treatment within th... [+7]

Status: Recruiting

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

The purpose of this study is to evaluate the efficacy and safety of ZL-1310 compared to Investigator's Choice Therapy in participants with relapsed Small Cell Lung Cancer.

Participants needed: 480
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Jun 23, 2026Locations: 66
Eligibility criteria

Age >/= 18 years, or considered an adult by local regulations, at the time of co... [+9]

Received more than one line of systemic therapy for Extensive-Stage SCLC. [+9]

Status: Recruiting

A Study of ZL-1310 in Participants With Selected Solid Tumors

A Phase 1b/2, Open-label, Multi-center Study of ZL-1310 in Participants With Selected Solid Tumors

Participants needed: 112
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: May 8, 2026Locations: 21
Eligibility criteria

Signed informed consent [+6]

Participants with another known malignancy that is progressing or requires activ... [+13]

Status: Recruiting

A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

An open-label, multicenter study of ZL-1310 as a single agent and in combination with Atezolizumab (with and without Carboplatin) to evaluate the safety, efficacy, and pharmacokinetics in subjects with small cell lung cancer

Participants needed: 339
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Apr 3, 2026Locations: 38
Eligibility criteria

Signed informed consent [+6]

Participants with another known malignancy that is progressing or requires activ... [+16]

Status: Recruiting

A Study to Assess the Efficacy and Safety of ZL-1109 in Chinese Participants With Active Thyroid Eye Disease

A Multicenter, Double-blinded, Randomized, Placebo-controlled Phase 3 Study of ZL-1109 in Chinese Participants with Thyroid Eye Disease (TED)

Participants needed: 99
Trial details
Phase: Phase 3Age: 18-75Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Dec 29, 2025Locations: 27
Eligibility criteria

Have moderate to severe TED [+3]

Have received prior treatment with another anti-IGF-1R mAb or anti-thyroid stimu... [+3]

Status: Recruiting

A Phase 1/1b Study to Evaluate Safety, Tolerability and Pharmacokinetics of ZL-1503 in Healthy Volunteers and Participants With Moderate to Severe Atopic Dermatitis

This is a phase 1/1b randomized, double blind, placebo-controlled, single dose escalation (SAD) and multiple dose escalation (MAD) study to evaluate the safety, tolerability, and pharmacokinetics (PK) of ZL-1503 in healthy volunteers and participants with moderate to severe atopic dermatitis (AD)

Participants needed: 84
Trial details
Phase: Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: Zai Lab (Shanghai) Co., Ltd.Updated: Dec 19, 2025Locations: 1
Eligibility criteria

Healthy male and female volunteers, 18-65 years of age [+11]

Significant health issues, such as positive tests for human immunodeficiency vir... [+9]