Clinical trials

3

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of the Efficacy and Safety of Cyclosporin Ophthalmic Gel in Subjects With Moderate to Severe Dry Eye Disease

This study is a multicenter, randomized, double-blind, placebo-controlled, superiority design Phase III clinical trial. The primary objective is to evaluate the efficacy and safety of cyclosporine ophthalmic gel versus placebo in the treatment of moderate to severe dry eye for 84 days.

Participants needed: 360
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.Updated: Jul 28, 2025Locations: 1
Eligibility criteria

aged ≥ 18 years old, males or females. [+7]

Subjects with severe dry eye requiring surgical treatment. [+9]

Status: Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Treatment With CsA-PG Ophthalmic Gel in Dry Eye Patients

This is a phase III, multicenter, randomized, double-masked, Active-controlled design. The aims to confirm previous findings of the efficacy and safety of CsA-PG Ophthalmic Gel by comparing it to CsA Ophthalmic Gel for treating dry eye symptoms.

Participants needed: 396
Trial details
Phase: Phase 3Age: 18+Biological sex: AllType: InterventionalSponsor: Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.Updated: Apr 29, 2025
Eligibility criteria

Be at least 18 years of age, male or female; [+6]

Clinical diagnosis or history of any clinically significant ocular diseases/diso... [+34]

Status: Recruiting

Efficacy and Safety of BRIMOCHOL PF and CARBACHOL PF in Chinese Presbyopia Patients

A multicenter, randomized, double-Blind, crossover, placebo-controlled Phase II clinical Study to evaluate the efficacy and safety of BRIMOCHOL PF and CARBACHOL PF in the treatment of Chinese patients with presbyopia.

Participants needed: 119
Trial details
Phase: Phase 2Age: 45-75Biological sex: AllType: InterventionalSponsor: Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.Updated: Apr 29, 2025Locations: 1
Eligibility criteria

At Visit 1 (Screening Period), the age ranges from 45 to 75 years old, regardles... [+7]

Use of corneal or scleral contact lenses within 28 days prior to screening or pl... [+11]