Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

GP350 CAR-T for Relapse/Refractory and Epstein-Barr Virus Infection Associated Lymphoid Neoplasms

This is a Phase 1/Phase 2 open-label, single-arm clinical study of GP350 CAR-T for Relapse/Refractory and Epstein-Barr virus infection associated lymphoid neoplasms. Each participant will undergo leukapheresis after enrolment, receive treatment of the conditioning chemotherapy, and an intravenous infusion of CAR-T cells. Each participant will proceed through the following study procedures: * Screening * Enrollment/Leukapheresis * Conditioning chemotherapy * CAR T treatment * Post-treatment assessment * Long-term follow-up

Participants needed: 24
Trial details
Phase: Phase 1, Phase 2Age: 18-70Biological sex: AllType: InterventionalSponsor: Zhimin ZhaiUpdated: Dec 29, 2025Locations: 1
Eligibility criteria

Diagnosis: Confirmed diagnosis of lymphoid neoplasms according to WHO-HAEM5 (Ala... [+18]

Active Infections: Presence of active hepatitis A, B, or C infection, or other u... [+15]

Status: Recruiting

EX02 CAR-T Cells for Relapsed and Refractory Acute Myeloid Leukemia

This is a early Phase 1 open-label, single-arm clinical study of EX02 CAR-T therapy for relapsed and refractory acute myeloid leukemia. Each participant will undergo leukapheresis after enrolment, receive treatment of the conditioning chemotherapy of cyclophosphamide and fludarabine, and an an intravenous infusion of CAR-T cells. Each participant will proceed through the following study procedures: * Screening * Enrollment/Leukapheresis * Conditioning chemotherapy * CAR T treatment * Post-treatment assessment * Long-term follow-up

Participants needed: 9
Trial details
Phase: Early Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: Zhimin ZhaiUpdated: Oct 15, 2024Locations: 1
Eligibility criteria

According to the Chinese Adult Acute Myeloid Leukemia (AML) Diagnosis and Treatm... [+6]

Active hepatitis A, B, C, HIV infection, or other severe active infections that... [+7]