Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Phase I/II Study to Evaluate the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects with Advanced Solid Tumors

This is a multicenter, open-label study to assess the safety and preliminary efficacy and to determine the maximum tolerated dose (MTD) or maximum administration dose (MAD) and recommended Phase 2 doses (RP2D) of PRJ1-3024 in subjects with relapsed/refractory solid tumors. The study consists of two parts, one is a 3+3 dose escalation study and another is a pharmaceutical extension of RP2D.

Participants needed: 267
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Zhuhai Yufan Biotechnologies Co., LtdUpdated: Dec 17, 2024Locations: 5
Eligibility criteria

Histologically or cytologically confirmed locally advanced (unresectable) or met... [+8]

History of another malignancy [+8]

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Status: Recruiting

A Phase Ib Study of PRJ1-3024 for Treatment of Advanced or Metastatic Melanoma

This is a Phase Ib, open-label study to determine the safety and preliminary efficacy of PRJ1-3024 in China subjects with unresectable local advanced or metastatic melanoma

Participants needed: 40
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Zhuhai Yufan Biotechnologies Co., LtdUpdated: Dec 11, 2024Locations: 1
Eligibility criteria

Male or non-pregnant, non-lactating female subjects aged ≥18 years. [+8]

Known symptomatic brain metastases requiring >10 mg/day of prednisolone. [+8]

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