Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Clinical Study on the Efficacy and Safety of Fasudil Hydrochloride Combined With Immunotherapy in the Treatment of Metastatic Castration-resistant Prostate Cancer

Carrying out clinical trials of salbutamol hydrochloride combined with immunotherapy and castration for the treatment of prostate cancer is of great significance. Firstly, it can verify the efficacy and safety of this combination in the treatment of prostate cancer, providing a scientific basis for its clinical application. Secondly, through clinical trials, the mechanism of action of salbutamol hydrochloride combined with immunotherapy can be further studied. Finally, this clinical trial can further expand the treatment strategies for prostate cancer.

Participants needed: 30
Trial details
Phase: Phase 2Age: 18-85Biological sex: MaleType: InterventionalSponsor: baotai LiangUpdated: Nov 26, 2025Locations: 1
Eligibility criteria

Age ≥ 18 years and < 85 years; [+3]

Severe cardiovascular and cerebrovascular diseases; [+6]

Status: Recruiting

Homoharringtonine Plus Androgen Deprivation Therapy in the Neoadjuvant Treatment of Prostate Cancer: A Single-Arm Clinical Study

The project aims to verify the therapeutic effect of neoadjuvant homoharringtonine combined with androgen deprivation therapy in patients with localized high-risk/very high-risk, regional lymph node-metastatic, or metastatic prostate cancer before radical prostatectomy through clinical trials, thereby identifying an effective treatment for patients with advanced prostate cancer.

Participants needed: 93
Trial details
Phase: Phase 2Age: 18-85Biological sex: MaleType: InterventionalSponsor: baotai LiangUpdated: Nov 18, 2025Locations: 1
Eligibility criteria

Histologically or cytologically confirmed prostate cancer; [+3]

A history of previous prostatectomy; [+2]

Status: Recruiting

Clinical Study of Fasudil Hydrochloride and PD1 Inhibitor Combined With Androgen Deprivation in Neoadjuvant Therapy of Prostate Cancer

The high incidence of prostate cancer is one of the important diseases that threaten the health of old men in our country. Although androgen deprivation therapy is an important treatment option for prostate cancer, although neoadjuvant androgen deprivation therapy combined with radical prostatectomy reduced the positive rate of surgical margins, it did not show statistically significant improvement in prostate-specific antigen (PSA). At the same time, few trials reported pathological complete response (pCR) and minimal residual lesion (MRD). The purpose of this project is to verify the therapeutic effect of fasudil hydrochloride and PD1 inhibitor combined with androgen deprivation in patients with locally advanced prostate cancer or oligometastatic prostate cancer before radical prostatectomy through randomized controlled clinical trials, so as to find an effective treatment for locally advanced prostate cancer or oligometastatic prostate cancer.

Participants needed: 83
Trial details
Phase: Phase 2, Phase 3Age: 18-85Biological sex: MaleType: InterventionalSponsor: baotai LiangUpdated: Nov 18, 2025Locations: 1
Eligibility criteria

① Age ≥18 years and ≤85 years; [+2]

①Any previous or ongoing PCa treatment, including radiotherapy, chemotherapy, AD... [+3]

Status: Recruiting

Clinical Study on Neoadjuvant Therapy of Homoharringtonine Combined With Androgen Deprivation for Prostate Cancer

The high incidence of prostate cancer is one of the important diseases that threaten the health of old men in our country. Although androgen deprivation therapy is an important treatment option for prostate cancer, although neoadjuvant androgen deprivation therapy combined with radical prostatectomy reduced the positive rate of surgical margins, it did not show statistically significant improvement in prostate-specific antigen (PSA). At the same time, few trials reported pathological complete response (pCR) and minimal residual lesion (MRD). The purpose of this project is to verify the therapeutic effect of homoharringtonine combined androgen deprivation in patients with locally advanced prostate cancer or oligometastatic prostate cancer before radical prostatectomy through a randomized controlled clinical trial, so as to find an effective treatment for locally advanced prostate cancer or oligometastatic prostate cancer.

Participants needed: 96
Trial details
Phase: Phase 2Age: 18-85Biological sex: MaleType: InterventionalSponsor: baotai LiangUpdated: Sep 8, 2025Locations: 2
Eligibility criteria

① Age ≥18 years and ≤85 years; [+2]

①Any previous or ongoing PCa treatment, including radiotherapy, chemotherapy, AD... [+3]

Status: Not yet recruiting

Clinical Study of Geranium Wilfordii Combined With Androgen Deprivation in Neoadjuvant Therapy of Prostate Cancer

The high incidence of prostate cancer is one of the important diseases that threaten the health of old men in our country. Although androgen deprivation therapy is an important treatment option for prostate cancer, although neoadjuvant androgen deprivation therapy combined with radical prostatectomy reduced the positive rate of surgical margins, it did not show statistically significant improvement in prostate-specific antigen (PSA). At the same time, few trials reported pathological complete response (pCR) and minimal residual lesion (MRD). The purpose of this project is to verify the efficacy of geranium combined with androgen deprivation in the treatment of locally advanced prostate cancer or oligometastatic prostate cancer before radical prostatectomy through randomized controlled clinical trials, so as to find an effective treatment for locally advanced prostate cancer or oligometastatic prostate cancer.

Participants needed: 95
Trial details
Phase: Phase 2, Phase 3Age: 18-85Biological sex: MaleType: InterventionalSponsor: baotai LiangUpdated: Mar 6, 2025
Eligibility criteria

① Age ≥18 years and ≤85 years; [+2]

①Any previous or ongoing PCa treatment, including radiotherapy, chemotherapy, AD... [+3]