Health Trials

Clinical trials

2

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Neoadjuvant Short-Course Radiotherapy With or Without Chemotherapy and AK112 in Locally Advanced Rectal Cancer

This phase II multicenter, randomized study evaluates the safety and efficacy of neoadjuvant short-course radiotherapy (SCRT) sequentially combined with AK112 (Envafolimab) with or without chemotherapy in patients with locally advanced rectal cancer (LARC). The study also aims to identify biomarkers predicting tumor response and develop efficacy prediction models.

Participants needed: 100
Trial details
Phase: Phase 2Age: 18-80Biological sex: AllType: InterventionalSponsor: fan liUpdated: Apr 10, 2025Locations: 1
Eligibility criteria

Signed written informed consent. [+6]

Allergy to monoclonal antibodies, AK112 components, or CapeOX regimen. [+1]

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Status: Not yet recruiting

No Stoma VS Ghost Stoma in Patients Undergoing Total Mesorectal Excision for Rectal Cancer

This study aimed at comparing the Comprehensive Complication Index (CCI), readmission rates, postoperative hospitalization days, duration of bearing the stoma (months), hospitalization costs, the number of hospitalizations with ghost ileostomy group versus no ileostomy group after total mesorectal excision for rectal cancer.

Participants needed: 500
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: fan liUpdated: Jan 26, 2024
Eligibility criteria

Pathologically confirmed rectal cancer. [+2]

ASA score >3. [+7]

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