Clinical trials

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Condition / disease
Location
Status: Recruiting

A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors

The goal of this clinical trial is to learn how roginolisib works in comparison to standard treatment in adult patients with Myelofibrosis. The main questions it aims to answer is to evaluate the safety and tolerability of roginolisib when administered in combination with ruxolitinib.

Participants needed: 26
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: iOncturaUpdated: Jun 23, 2026Locations: 12
Eligibility criteria

≥18 years of age inclusive, at the time of signing the informed consent. [+11]

Inability to swallow food or any condition of the upper gastrointestinal tract t... [+25]