Clinical trials

6

Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

This Clinical Trial is Designed to Evaluate the Safety, Tolerability, Feasibility and Preliminary Efficacy of NouvNeu001 (Human Dopaminergic Progenitor Cells Injection) in Patients With Parkinson's Disease.

This is a phase 1/2 clinical study to evaluate the safety, tolerability, feasibility, and preliminary efficacy of NouvNeu001 in patients with advanced Parkinson's Disease.

Participants needed: 5
Trial details
Phase: Phase 1, Phase 2Age: 30-75Biological sex: AllType: InterventionalSponsor: iRegene Therapeutics Co., Ltd.Updated: May 11, 2026Locations: 1
Eligibility criteria

Diagnosis of PD between past 4 to 20 years (meet MDS 2015 clinical diagnostic cr... [+18]

Atypical Parkinsonism (Parkinsonism-Plus syndrome, secondary parkinsonism, famil... [+48]

Status: Not yet recruiting

Phase I Clinical Study of NouvNeu001 Injection for the Treatment of Moderate-to-Advanced Parkinson's Disease in Patients Who Have Previously Undergone Deep Brain Stimulation or Deep Brain Nucleus Lesioning Surgery

This clinical trial is designed to evaluate the safety, tolerability and preliminary efficacy of a single injection of NouvNeu001 (Human Dopaminergic Progenitor Cells Injection) in patients with Parkinson's Disease who have previously undergone deep brain stimulation or deep brain nucleus lesioning surgery.

Participants needed: 10
Trial details
Phase: Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: iRegene Therapeutics Co., Ltd.Updated: Apr 24, 2026Locations: 1
Eligibility criteria

Age ≥18 years and ≤70 years, male or female. [+10]

Atypical or secondary parkinsonism confirmed by the investigator to be caused by... [+21]

Status: Recruiting

A Phase I/III Clinical Study to Evaluate NouvNeu001 Injection for Multiple System Atrophy

This clinical trial is designed to evaluate the safety, tolerability and preliminary efficacy of a single injection of NouvNeu001 (Human Dopaminergic Progenitor Cells Injection) in patients with Multiple System Atrophy.

Participants needed: 9
Trial details
Phase: Phase 1Age: 30-70Biological sex: AllType: InterventionalSponsor: iRegene Therapeutics Co., Ltd.Updated: Apr 14, 2026Locations: 1
Eligibility criteria

Aged between 30 and 70 years (inclusive), regardless of gender. [+7]

Neurological diseases/disorders other than Multiple System Atrophy, such as Park... [+19]

Status: Not yet recruiting

The Safety, Feasibility and Efficacy of NouvNeu001 for Parkinson's Disease

This clinical trial is designed to evaluate the safety, tolerability and preliminary efficacy of a single injection of NouvNeu001 (Human Dopaminergic Progenitor Cells Injection) in patients with Parkinson's disease.

Participants needed: 30
Trial details
Phase: Phase 2Age: 50-75Biological sex: AllType: InterventionalSponsor: iRegene Therapeutics Co., Ltd.Updated: Jun 29, 2025Locations: 1
Eligibility criteria

Age 50-75 years old, male or female [+11]

Atypical or secondary Parkinson's syndrome to be caused by drugs, metabolic diso... [+20]

Status: Recruiting

The Safety, Tolerability and Preliminary Efficacy of NouvNeu001 for Early-onset Parkinson's Disease

The goal of this clinical trial is to learn about the safety of NouvNeu001 injection in Early-onset Parkinson's Disease (EOPD) patients. It will also learn about the effects of NouvNeu001 treatment. The main questions it aims to answer are: What medical problems do participants have when transplanting NouvNeu001 into bilateral putamen using stereotactic neurosurgery? Does injection of NouvNeu001 improve the motor function and non-motor function in participants? Participants will: Be injectioned the NouvNeu001 into bilateral putamen using stereotactic neurosurgery. Take immunosuppressants to prevent potential immune rejection for 24 to 36 weeks.

Participants needed: 6
Trial details
Phase: Phase 1Age: 18-70Biological sex: AllType: InterventionalSponsor: iRegene Therapeutics Co., Ltd.Updated: Nov 7, 2024Locations: 1
Eligibility criteria

Age 18-70 years old, male or female [+6]

Atypical Parkinsonism [+23]

Status: Recruiting

The Safety, Tolerability and Efficacy of NouvNeu001 for Parkinson's Disease

This clinical trial is designed to evaluate the safety, tolerability and preliminary efficacy of a single injection of NouvNeu001 (Human Dopaminergic Progenitor Cells Injection) in patients with Parkinson's disease.

Participants needed: 40
Trial details
Phase: Phase 1, Phase 2Age: 50-75Biological sex: AllType: InterventionalSponsor: iRegene Therapeutics Co., Ltd.Updated: Nov 1, 2024Locations: 2
Eligibility criteria

Age 50-75 years old, male or female [+7]

Atypical Parkinsonism [+24]