A 2×2 Factorial Randomized Controlled Trial for ERCP
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60+
SponsorGang Chen
About this trial
To investigate the effects of propofol vs. cyclopropofol and sufentanil vs. esketamine on intraoperative hypoxemia and hypotension in elderly patients undergoing ERCP, as well as the interaction between these two factors.
Eligibility criteria
Qualifiers
Age ≥ 60 years old.
ASA II-III level.
BMI<30kg/m2.
Patients who require elective therapeutic ERCP.
Disqualifiers
Previous anatomical changes in the gastrointestinal tract, delayed gastric emptying, and gastric outlet obstruction.
Coagulation dysfunction or tendency towards nosebleeds.
Combined severe heart disease (coronary heart disease, myocardial infarction, congestive heart failure, left ventricular ejection fraction<40%, tachyarrhythmia)
Have a history of allergies to relevant anesthetic drugs in the past.
Trial design
Treatments tested in this trial
- Anesthesia induction using propofol+sufentanil
- Anesthesia induction using propofol+esketamine
- Anesthesia induction using ciprofol+sufentanil
- Anesthesia induction using ciprofol+es-ketamine
Treatment groups
236 Participants
are divided into 4 treatment groupsLocations
Sponsors and collaborators
Gang Chen
Lead sponsor
Sir Run Run Shaw Hospital
Sponsor institution
Source ClinicalTrials.gov