A Randomized Controlled Trial Evaluating the Effectiveness of a Novel Risk-Stratified Screening Strategy for Lung Cancer

ConditionLung Cancer Screening

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age40-74

SponsorThe First Affiliated Hospital of Guangzhou Medical University

About this trial

A nationwide population-based multi-center RCT enrolling ≥60,000 eligible residents to compare screening effectiveness between risk-prediction-model-driven and traditional guideline-based high-risk lung cancer screening strategies.

Eligibility criteria

Qualifiers

Residents with local household registration residing continuously in the region for ≥3 years.

Aged 40-74 years at enrollment.

Disqualifiers

Prior diagnosis of lung cancer (histologically/cytologically confirmed)

Currently receiving active treatment for any malignancy.

Presence of severe comorbidities with life expectancy <5 years

Participation in any lung cancer screening program within 5 years.

Trial design

Treatments tested in this trial

Prediction Model Arm
Standard Screening Arm

Treatment groups

60,000 Participants

are divided into 2 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

The First Affiliated Hospital of Guangzhou Medical University

Lead sponsor

Source ClinicalTrials.gov