A Study of Females With CF Throughout Pregnancy and Post-partum, and Follow up of Their Offspring

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorRoyal Brompton & Harefield NHS Foundation Trust

About this trial

In this study, investigators aim to study in detail the physical (including nutritional and pulmonary) and mental health of females with cystic fibrosis (CF) planning a pregnancy, during pregnancy, and in the early parenthood period.

Additionally the health of offspring in infancy and early life will be studied to understand if further screening investigations or clinical care models should be part of clinical guidelines

Eligibility criteria

Qualifiers

Written informed consent obtained from participant.

Under the care of Royal Brompton Hospital CF Reproductive and Maternal Health Service

Age 16 years or above at time of recruitment

Confirmed diagnosis of CF

Disqualifiers

Any significant health condition which would cause inability to comply with protocol based on investigator discretion.

History of lung transplantation

Legal guardians' inability to provide consent to participate in the study.

Mother of infant has significant comorbidities unrelated to CF which could affect infant outcomes based on investigator discretion.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

60 Participants
are grouped into 3 trial groups

Sponsors and collaborators

Royal Brompton & Harefield NHS Foundation Trust

Lead sponsor

Cystic Fibrosis Trust

Collaborator

King's College London

Collaborator

Imperial College London

Collaborator