About this trial
This purpose of this study is to compare a new form of LASIK called Ray Tracing Guided LASIK to 3 other forms of corneal refractive surgery: 1. KLEx (KeratoLenticule Extraction) using the Zeiss Visumax 800 Laser, 2. WFO LASIK (Wavefront Optimized LASIK) using the Alcon EX500 Laser, and 3. Topography Guided LASIK (Contoura LASIK) also using the Alcon EX500 Laser.
Eligibility criteria
Qualifiers
Age 22-50 at the time of consent
Diagnosis of myopia or myopia with astigmatism with Preoperative manifest spherical equivalent refraction of ≥ -2.00 and ≤ -9.00 D (-2.00 D through -9.00 D)
Preop Spherical component of ≥ -2.00 and ≤ -8.00 D (-2.00 D through -8.00 D)
Refractive Cylinder of ≤ -3.00 D (0.00 through -3.00 D)
Disqualifiers
Clinically significant dry eye on clinical examination, as determined by the investigator
Irregular astigmatism, keratoconus, keratoconus suspect, or abnormal corneal tomography
History of corneal dystrophies or guttata
History of herpetic keratitis or active disease
Trial design
Treatments tested in this trial
- Ray-Tracing Guided LASIK
- Keratorefractive Lenticule Extraction (KLEx)
- WaveFront Optimized LASIK
- Topography Guided LASIK
Treatment groups
6
Treatment groupsSee each treatment group below.