About this trial
This study aims to compare the acute effects on hypoalgesia of training to failure using blood flow restriction (BFR) with dynamic occlusion versus BFR with fixed occlusion in patients with severe gonarthrosis. Two different training conditions will be performed with varying levels of blood flow occlusion (%BFR) and percentage of load (%RM): 1) 30% RM and 50% BFR with dynamic pressure; 2) 30% RM and 50% BFR with fixed pressure. Each participant will complete two individual sessions under different training conditions, randomly assigned with a 72-hour interval between sessions.
Eligibility criteria
Qualifiers
Age between 50 and 85 years
Diagnosis of severe gonarthrosis according to the clinical and radiographic criteria of the American College of Rheumatology guidelines.
On the waiting list for unilateral total knee replacement (TKR) surgery
Disqualifiers
Pain in the contralateral leg with an intensity ≥80/100 mm on the visual analog scale (VAS) during daily activities.
Previous hip or knee replacement surgery and osteotomy within the last year.
Autoimmune arthritis
Medical conditions that contraindicate exercise.
Trial design
Treatments tested in this trial
- Low-intensity resistance exercise to failure with moderate arterial occlusion pressure and dynamic pressure.
- Low-intensity resistance exercise to failure with moderate arterial occlusion pressure and fixed pressure.