The overall aim of this study is to investigate the effects of exercise on the amount of glucose that is made by the liver in people with and without Type 2 diabetes (T2D) and hepatic steatosis (fatty liver).
Provision of signed and dated informed consent form
Stated willingness to comply with all study procedures and availability for the duration of the study
Male or (pre-menopausal) female, aged 25-55 years
Body mass index (BMI) between 25 and 45 kg/m2
Exclusion criteria for individuals with T2D and elevated liver fat ≥5.6% Currently taking insulin, incretin mimetics, and/or thiazolidinediones
Any change in glucose-lowering medications within the previous three months.
Inability to stop any medications which interfere with glucose metabolism for visits 4 and 7.
Resting blood pressure ≥ 160/100 mm Hg