About this trial
Investigators hypothesize that the use of a human coach-supported digital/AI personal health assistant (app) will improve adherence to cholesterol-lowering medications (statins with or without ezetimibe) among patients with hyperlipidaemia and suboptimal LDL-C control, when compared to standard care.
Eligibility criteria
Qualifiers
Between 21 to 84 years old
Prescribed statins with or without ezetimibe for hyperlipidaemia.
Medication non-adherence as defined by the "Extent to Non-adherence" sub-scale of the DOSE Non-Adherence Measure), with a score > 1 (range from 0-15)
Singapore residents (citizens, permanent residents, or long-term pass holders).
Disqualifiers
Does not read or understand English. Current use of smartphone medication adherence app(s) that include statins.
Concurrent use of PCSK9 Inhibitors in addition to statins and/or ezetimibe
Participation in another study that uses medications that could affect lipid levels
Severe renal impairment defined as chronic kidney disease stage 4 and above.
Trial design
Treatments tested in this trial
- Human Coach-supported Digital/AI Personal Health Assistant to Improve Adherence to Lipid-Lowering Medications
Treatment groups
Sponsors and collaborators
National University of Singapore
Lead sponsor
National University Polyclinics, Singapore
Collaborator
Nanyang Technological University
Collaborator
National Healthcare Group Polyclinics
Collaborator
Consortium for Clinical Research and Innovation, Singapore (CRIS)
Collaborator
National University Heart Centre, Singapore
Collaborator