AdLip: Human Coach-supported Digital/AI Personal Health Assistant to Improve Adherence to Lipid-Lowering Medication

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-84
SponsorNational University of Singapore

About this trial

Investigators hypothesize that the use of a human coach-supported digital/AI personal health assistant (app) will improve adherence to cholesterol-lowering medications (statins with or without ezetimibe) among patients with hyperlipidaemia and suboptimal LDL-C control, when compared to standard care.

Eligibility criteria

Qualifiers

Between 21 to 84 years old

Prescribed statins with or without ezetimibe for hyperlipidaemia.

Medication non-adherence as defined by the "Extent to Non-adherence" sub-scale of the DOSE Non-Adherence Measure), with a score > 1 (range from 0-15)

Singapore residents (citizens, permanent residents, or long-term pass holders).

Disqualifiers

Does not read or understand English. Current use of smartphone medication adherence app(s) that include statins.

Concurrent use of PCSK9 Inhibitors in addition to statins and/or ezetimibe

Participation in another study that uses medications that could affect lipid levels

Severe renal impairment defined as chronic kidney disease stage 4 and above.

Trial design

Treatments tested in this trial

  • Human Coach-supported Digital/AI Personal Health Assistant to Improve Adherence to Lipid-Lowering Medications

Treatment groups

450 Participants
are divided into 2 treatment groups

Sponsors and collaborators

National University of Singapore

Lead sponsor

National University Polyclinics, Singapore

Collaborator

Nanyang Technological University

Collaborator

National Healthcare Group Polyclinics

Collaborator

Consortium for Clinical Research and Innovation, Singapore (CRIS)

Collaborator

National University Heart Centre, Singapore

Collaborator