About this trial
The goal of this clinical trial is to test two advices on alcohol drinking in more than 10.000 Spanish adult drinkers (men of 50 or more years and women of 55 or more years).
The main question it aims to answer is to test the non-inferiority advice of a moderate alcohol drinking pattern on all-cause mortality and other chronic disease like cardiovascular disease, cancer or type 2 diabetes.
Participants will receive during 4 years an advice to drink alcohol following a Mediterranean Alcohol Drinking Pattern (MADP): consuming alcohol in moderation, avoidance of binge drinking and preference for red wine.
Researchers will compare those who will receive a MADP advice with those who will receive an advice on abstention to see if the advice on MADP is not inferior than the abstention advice to prevent all-cause mortality and other chronic diseases.
Eligibility criteria
Qualifiers
Males aged 50-70 years, Women aged 55-75 years
Drinkers of any alcoholic beverage initially consuming 3 or more but 40 or less drinks/wk
Projected life expectancy more than 5 years (according to the judgment of their attending physician)
Willing to receive advice during up to 4 years on how to improve their alcohol intake making it healthier
Disqualifiers
Participants without smartphone or a computer (or tablet) with Internet connection.
Drinkers of less than 30 g of pure alcohol/wk or more than 400 g of pure alcohol/wk
Illiteracy, inability/unwillingness to give written consent or communicate with study staff, or inadequate abilities for the use of on-line technologies
Participants with any sever psychiatric condition or with a diagnosis of cognitive impairment or dementia.
Trial design
Treatments tested in this trial
- Moderate Alcohol Drinking Pattern
- Abstention