Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorThe University of Texas Health Science Center, Houston

About this trial

This is an observational study to understand the changes in alveolar dead space in medical critically ill patients with severe infection (severe sepsis) requiring mechanical ventilation and the possibility to predict multi-organ failure.

The measurement of alveolar dead space used to require sophisticated equipment and time. New ventilators have microprocessors that allow rapid mathematical calculation with minimal intervention.

Eligibility criteria

Qualifiers

Adults with severe sepsis or septic shock on mechanical ventilation

Enrolled in the initial six hours of ICU admission

Disqualifiers

Patients with withdrawal or hospice order.

Patients with terminal, irreversible disease, expect to decease in 48 hours from ICU admission.

Patients with COPD.

Patients transferred from outside ICU with ongoing sepsis management for more than six hours.

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

30 Participants
are grouped into 1 trial group