Analgesic Efficacy of Bupivacaine Infiltration, Erector Spinae Plane Block, and Intrathecal Morphine in Laparoscopic Cholecystectomy

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorAtaturk University

About this trial

This study is designed to compare three different methods of pain control after laparoscopic gallbladder surgery (laparoscopic cholecystectomy). Although this surgery is minimally invasive, participants often experience different types of pain after the operation, such as pain at the incision site, pain inside the abdomen, and shoulder pain caused by the gas used during surgery.

The investigators will compare three commonly used pain relief techniques:

Local infiltration - injecting a numbing medicine (bupivacaine) into the gallbladder bed and at the sites where the surgical instruments are placed.

Erector spinae plane (ESP) block - an ultrasound-guided nerve block performed in the back to reduce both abdominal and incisional pain.

Intrathecal morphine - a very small dose of morphine given into the spinal fluid before surgery to provide long-lasting pain relief.

The goal is to determine which method provides the best pain control, reduces the need for opioid medications, and improves recovery after surgery.

Eligibility criteria

Qualifiers

Adults aged 18-65 years

Scheduled for elective laparoscopic cholecystectomy

American Society of Anesthesiologists (ASA) physical status I-III

Able to provide written informed consent

Disqualifiers

Body mass index (BMI) > 35 kg/m²

History of coagulopathy or bleeding disorders

Known allergy or hypersensitivity to opioids or local anesthetics

Chronic pain or regular analgesic use

Trial design

Treatments tested in this trial

  • Bupivacaine Infiltration
  • Erector Spinae Plane Block
  • Intrathecal Morphine

Treatment groups

132 Participants
are divided into 3 treatment groups

Sponsors and collaborators